多指标综合平衡法-正交试验优化九蒸九晒地黄炮制工艺 点击下载
论文标题: 多指标综合平衡法-正交试验优化九蒸九晒地黄炮制工艺
英文标题:
中文摘要: 目的:对九蒸九晒地黄炮制工艺进行优选。方法:采用L9(34)正交试验设计,以5-羟甲基糠醛、毛蕊花糖苷、还原性糖、水浸出物含量及性状评分为指标,考察加酒量、蒸制时间、干燥方式3个因素对炮制工艺的影响,采用综合平衡法进行结果评价并对优化工艺进行验证。结果:最优炮制工艺条件为加黄酒量40%,反复9次蒸制、每次蒸制6 h,70 ℃鼓风干燥。验证试验中各指标平均值分别为4.030 mg/g、0.117 mg/g、0.376 7g/g、0.733 g/g、9.0分,RSD分别为1.78%、2.9%、1.54%、2.13%、0.1%(n=3)。结论:优化工艺合理,成品质量具有可控性,可为九蒸九晒地黄质量控制研究提供参考。
英文摘要: OBJECTIVE: To optimize the processing technology of nine steaming nine drying of Rehmannia glutinosa. METHODS: L9(34) orthogonal experimental design was adopted to investigate the effects of the amount of added wine, steaming time and drying way on processing technology using the content and property of 5-hydroxymethyl furfural, acteoside, reducing sugar water extract, and character score as indexes. Comprehensive balance method was used for result evaluation, and optimized technology was validated. RESULTS: The optimized processing condition was as follows as the amount of added yellow wine 40%, steaming for 9 times, lasting for 6 h each time, blast drying at 70 ℃. Average value of each factor in validation test was 4.030 mg/g, 0.117 mg/g, 0.376 7 g/g, 0.733 g/g and 9.0 points, respectively. Their RSDs were 1.78%, 2.9%, 1.54%, 2.13% and 0.1%(n=3). CONCLUSIONS: Optimized technology is reasonable and controllable in product quality, and can provide reference for quality control study of nine steaming nine drying of R. glutinosa.
期刊: 2016年第27卷第7期
作者: 张静,马瑛
英文作者: ZHANG Jing,MA Ying
关键字: 九蒸九晒;地黄;炮制工艺;正交试验;综合平衡法;5-羟甲基糠醛;毛蕊花糖苷;还原性糖
KEYWORDS: Nine steaming nine drying; Rehmannia glutinosa; Processing technology; Orthogonal test; Comprehensive balance method; 5-hydroxymethyl furfural; Acteoside; Reducing sugar
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