索他洛尔致心力衰竭高龄患者QT间期延长的药学监护 点击下载
论文标题: 索他洛尔致心力衰竭高龄患者QT间期延长的药学监护
英文标题:
中文摘要: 目的:探讨临床药师在预防及处理索他洛尔致心力衰竭高龄患者QT间期延长中的作用。方法:临床药师参与1例心力衰竭高龄患者的药物治疗,协助医师识别并评估索他洛尔致QT间期延长的风险,根据患者临床症状和实验室检查指标先后建议继续使用索他洛尔抗心律失常,调整护肝药物的应用,并行心电监护、电解质水平监测及用药教育等药学监护。结果:医师采纳临床药师建议,患者病情好转,未出现恶性心律失常,11 d后出院。结论:心力衰竭高危患者的药物治疗应以改善心功能、维持血流动力学的稳定为主;临床药师可结合相关指南和文献,协助医师及时识别致QT间期延长的药物,评估发生尖端扭转型室性心动过速等不良后果的风险,共同制订和优化用药方案,加强药学监护,以保证治疗的安全、有效。
英文摘要: OBJECTIVE: To explore the role of clinical pharmacists participating in the prevention and treatment of sotalol-induced QT prolongation in aged patient with heart failure. METHODS: Clinical pharmacists participated in the treatment for a aged patient with heart failure, and assisted physicians to identify and assess the risk of sotalol-induced QT prolongation. According to the clinical symptoms and laboratory indexes, it was suggested to continue to use sotalol for antiarrhythmic, adjust the hepatoprotective drug, given pharmaceutical care of ECG, electrolyte level monitoring, drug education and so on. RESULTS: Physicians adopted the suggestions of clinical pharmacists to relive the illness without malignant arrhythmia and discharged after 11 d. CONCLUSIONS: The patient with heart failure should be dominated by improving cardiac function and maintaining hemodynamic stability; combined with related guidelines and documentation, clinical pharmacists can assist physicians to identify the drug that induced QT prolongation, asses the risk of torsades de pointes ventricular tachycardia and other bad consequences, develop and optimize the regimen and strengthen pharmaceutical care to ensure the safe and effective treatment.
期刊: 2016年第27卷第23期
作者: 赖晓东,许珊,谢飞
英文作者: LAI Xiaodong,XU Shan,XIE Fei
关键字: 心力衰竭;肝肾功能不全;QT间期延长;索他洛尔;药品不良反应;药学监护
KEYWORDS: Heart failure; Hepatic/renal insufficiency; QT prolongation; Sotalol; Adverse drug reaction; Pharmaceutical care
总下载数: 81次
本日下载数: 2次
本月下载数: 81次
文件大小: 619.60Kb

* 注:未经本站明确许可,任何网站不得非法盗链资源下载连接及抄袭本站原创内容资源!在此感谢您的支持与合作!