天麻对高血压的药理作用机制研究进展 点击下载
| 论文标题： | 天麻对高血压的药理作用机制研究进展 |
| 英文标题： | |
| 中文摘要： | 天麻作为传统平肝息风类中药，其主要活性成分包括天麻素、天麻多糖、天麻苷元等，具有息风止痉、平抑肝阳、祛风通络之功，与高血压的中医病机高度契合。本文系统综述天麻活性成分、配伍药对及经典复方对高血压的药理作用与分子机制，发现天麻及其活性成分可调控血流动力学、氧化应激和炎症反应等多途径协同发挥降压作用，减轻高血压血管损伤，改善高血压所致心、脑、肾等靶器官损伤。天麻与钩藤、川芎、丹参等药材配伍可针对高血压表现出显著的协同增效作用。天麻钩藤饮、半夏白术天麻汤等含天麻经典复方可通过抗炎、抗氧化、保护血管内皮，改善高血压血管损伤、降低血压。 |
| 英文摘要： | As a traditional Chinese medicinal herb for pacifying the liver and extinguishing wind， Gastrodiae Rhizoma contains main active ingredients such as gastrodin， gastrodia polysaccharides and gastrodigenin. It exerts the effects of extinguishing wind and relieving convulsions， calming liver yang， dispelling wind and unblocking collaterals， which is highly consistent with the traditional Chinese medicine pathogenesis of hypertension. This paper systematically reviews the pharmacological effects and molecular mechanisms of active ingredients of Gastrodiae Rhizoma， herb pair compatibility， and classic prescriptions in hypertension. It is found that Gastrodiae Rhizoma and its active ingredients can collaboratively exert antihypertensive effects by regulating hemodynamics， oxidative stress， inflammatory response and other pathways， alleviate hypertensive vascular injury， and ameliorate damage to target organs including the heart， brain and kidney induced by hypertension. Compatibility of Gastrodiae Rhizoma with medicinal materials such as Uncaria， Chuanxiong， and Danshen produces remarkable synergistic efficacy against hypertension. Classic prescriptions containing Gastrodiae Rhizoma represented by Tianma gouteng decoction and Banxia baizhu tianma decoction can inhibit inflammation， resist oxidation， and protect vascular endothelium， so as to ameliorate hypertensive vascular injury and lower blood pressure. |
| 期刊： | 2026年第37卷第13期 |
| 作者： | 黄曦渝；罗国胜；朱玢；贺哲学；黄永光；周家福 |
| 英文作者： | HUANG Xiyu，LUO Guosheng，ZHU Bin，HE Zhexue，HUANG Yongguang，ZHOU Jiafu |
| 关键字： | 天麻; 高血压; 活性成分; 药对; 复方 |
| KEYWORDS： | Gastrodiae Rhizoma; hypertension; active ingredients; herb pairs; prescriptions |
| 总下载数： | 81次 |
| 本日下载数： | 2次 |
| 本月下载数： | 81次 |
| 文件大小： | 619.60Kb |
* 注：未经本站明确许可，任何网站不得非法盗链资源下载连接及抄袭本站原创内容资源!在此感谢您的支持与合作！