生血宁片治疗妊娠期缺铁性贫血疗效的Meta分析 点击下载
论文标题: 生血宁片治疗妊娠期缺铁性贫血疗效的Meta分析
英文标题:
中文摘要: 目的:系统评价生血宁片治疗妊娠期缺铁性贫血的疗效,为临床提供循证参考。方法:计算机检索中国知网、万方、维普、PubMed等数据库中2008-2018年发表的关于生血宁片治疗妊娠期缺铁性贫血的临床随机对照试验(RCT),筛选文献、提取资料并采用改良后的Jadad评分量表评价纳入研究的质量,采用Stata 12.0软件进行Meta分析。结果:共纳入11项RCT,合计1 617例患者。生血宁片的总有效率均显著高于硫酸亚铁[OR=8.73,95%CI(2.96,25.69),P<0.05]、琥珀酸亚铁[OR=1.86,95%CI(1.04,3.33),P<0.05]和膳食调理[OR=3.43,95%CI(2.08,5.66),P<0.05],差异均有统计学意义。结论:生血宁片治疗妊娠期缺铁性贫血的疗效显著优于常规补铁剂。
英文摘要: OBJECTIVE: To evaluate therapeutic efficacy of Shengxuening tablets in the treatment of iron-deficiency anemia during pregnancy, so as to provide evidence for clinical decisions. METHODS: Retrieved from CNKI, Wanfang, VIP and PubMed, clinical randomized controlled trials (RCTs) about Shengxuening tablets in the treatment of iron-deficiency anemia during pregnancy were collected during 2008-2018. After screening literatures and extracted information, the literature quality was evaluated by using improved Jadad scale. Meta-analyses was performed by using Stata 12.0 software. RESULTS: A total of 11 RCTs were included, inulving 1 617 patients. Total response rate of Shengxuening tablets was significantly higher than those of ferrous sulfate [OR=8.73,95%CI(2.964,25.69),P<0.05], ferrous succinate [OR=1.86,95%CI(1.04,3.33),P<0.05] and dietory conditioning [OR=3.43,95%CI(2.08,5.66),P<0.05], with statistical significance. CONCLUSIONS: Therapeutic efficacy of Shengxuening tablets is significantly better than that of routine iron supplements in the treatment of iron-deficiency anemia during pregnancy.
期刊: 2018年第29卷第12期
作者: 陈帆,刘微微,刘巧艳,曹世义
英文作者: CHEN Fan,LIU Weiwei,LIU Qiaoyan,CAO Shiyi
关键字: 生血宁片;妊娠期缺铁性贫血;随机对照试验;Meta分析
KEYWORDS: Shengxuening tablets; Iron-deficiency anemia during pregnancy; Randomized controlled trial; Meta-analysis
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