益心舒胶囊辅助治疗冠心病心绞痛有效性的Meta分析 点击下载
论文标题: 益心舒胶囊辅助治疗冠心病心绞痛有效性的Meta分析
英文标题:
中文摘要:

目的:系统评价益心舒胶囊辅助治疗冠心病心绞痛的有效性,以为临床提供循证参考。方法:计算机检索中国期刊全文

数据库、中文科技期刊数据库、万方数据库、Medline 和EMBase,收集益心舒胶囊(试验组)对比其他药物(对照组)辅助治疗冠心病

心绞痛有效性的随机对照试验(RCT),对符合纳入标准的临床研究进行资料提取,并采用改良后的Jadad 量表进行质量评价,采用

Rev Man 5.2 统计软件进行Meta 分析。结果:共纳入11 项RCT,合计1 827 例患者。Meta 分析结果显示,试验组患者心绞痛改善

总有效率[OR=0.30,95%CI(0.23,0.40),P<0.001]、心电图改善总有效率[OR=0.52,95%CI(0.41,0.66),P<0.001]均显著高于对

照组,差异有统计学意义。结论:益心舒胶囊辅助治疗冠心病心绞痛的有效性较好。

英文摘要:

OBJECTIVE:Tosystematically evaluate the efficacy of Yixinshu capsule in the adjuvant treatmentof angina pectoris,

and provide evidence-based reference for clinical treatment. METHODS:Retrieved from CJFD,VIP Database,Wanfang Database,

Medline and EMBase,randomized controlled trials(RCT)about the efficacyof Yixinshu capsule(test group)versus other drugs

(control group)in the adjuvant treatment of angina pectoris were collected. Meta-analysis was performed bu using Rev Man 5.2

software after data extraction and quality evaluation by modified Jadad. RESULTS:Totally 11 RCTs were enrolled,involving 1 827 patients.

Results of Meta-analysis showed the total effective rate of angina pectoris improvement [OR=0.30,95%CI(0.23,0.40),P<

0.001] and electrocardiogram improvement [OR=0.52,95%CI(0.41,0.66),P<0.001] in test group were significantly higher than

control group,there was significant difference between 2 groups. CONCLUSIONS:Yixinshu is effective for the adjuvant treatment

of angina pectoris.

期刊: 2016年第27卷第3期
作者: 唐文,谭建玲,贾亮亮,金桂兰
英文作者: TANG Wen,TAN Jianling,JIA Liangliang,JIN Guilan
关键字: 益心舒胶囊;冠心病心绞痛;有效性;Meta分析
KEYWORDS: Yixinshu capsule;Angina pectoris;Effectiveness;Meta-analysis
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