1例乳腺癌合并静脉血栓栓塞患者的抗凝方案优化 点击下载
论文标题: 1例乳腺癌合并静脉血栓栓塞患者的抗凝方案优化
英文标题:
中文摘要: 目的:探讨临床药师对乳腺癌合并下肢静脉血栓栓塞(VTE)患者抗凝方案的优化方法和作用。方法:临床药师参与1例乳腺癌合并下肢VTE患者的药物治疗过程,建议给予患者低分子肝素钠0.6 ml,sc,qd初始抗凝方案后,采用华法林钠片3 mg,po,qd的口服剂型抗凝方案;在用药变更期采用叠加交替的方式进行,并对患者实施药学监护和用药教育。结果:医师采纳临床药师建议,患者经过27 d的抗凝治疗和单次紫杉醇化疗,凝血功能国际标准化比值为2.71。患者无特殊不适并出院。结论:临床药师参与患者个体化抗凝方案的优化和药学监护,促进了医师的合理用药,协助临床防范严重药品不良反应发生,保障了患者用药安全,提高了患者的用药依从性。
英文摘要: OBJECTIVE: To explore optimization method and effect of clinical pharmacists on anticoagulants therapy plan for cancer patient with venous thromboembolism (VTE). METHODS: Clinical pharmacists participated in the whole process of anticoagulant therapy for one case of breast cancer complicated with VTE. Clinical pharmacists suggested patient to initially take low molecular weight heparin sodium 0.6 ml,sc,qd; and then take Warfarin sodium tablet 3 mg,po,qd; initial plan and oral dosage form plan superimposed and alternated, and pharmaceutical care and medication education were also provided for the patient. RESULTS: Physicians adopted clinical pharmacist’s suggestions, and the patient received anticoagulant therapy for 27 days and paclitaxel chemotherapy once. Coagulation function INR was 2.71; the patient didn’t felt discomfort and then discharged from hospital. CONCLUSIONS: The participation of clinical pharmacists in the optimization of individualized anticoagulant therapy and pharmaceutical care is able to promote rational drug use, prevent severe ADR in the clinic, guarantee the safety of drug use and improve medication compliance.
期刊: 2016年第27卷第5期
作者: 李晨露,潘宏铭,沈丽蓉,邵华
英文作者: LI Chenlu,PAN Hongming,SHEN Lirong,SHAO Hua
关键字: 乳腺癌;静脉血栓栓塞;华法林;临床药师;药学监护
KEYWORDS: Breast cancer; Venous thromboembolism; Warfarin; Clinical pharmacist; Pharmaceutical care
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