我院药师干预剖宫产术预防使用抗菌药物的回顾性分析 点击下载
论文标题: 我院药师干预剖宫产术预防使用抗菌药物的回顾性分析
英文标题:
中文摘要: 目的:为剖宫产术合理预防使用抗菌药物提供参考。方法:回顾性调查我院2013年1-12月(干预前)手术开始前0.5~2 h给予预防用药的剖宫产术患者472例及2014年1-12月(干预后)钳夹脐带后给予抗菌药物的剖宫产术患者431例,对其抗菌药物使用情况进行统计分析。结果:干预后,预防用药给药时机合理率为100%,选择药物品种合理率从64.41%上升至93.50%,预防用药疗程合理率从50.21%上升至92.11%,用法用量合理率也有了明显改善,与干预前比较差异均有统计学意义(P<0.05)。干预后,人均抗菌药物费用从(103.25±13.62)元下降至(54.61±27.21)元,人均住院费用从(5 574.8±117.6)元下降至(5 427.4±106.7)元,与干预前比较差异均有统计学意义(P<0.05)。结论:临床药师通过药学干预, 能明显提高剖宫产术预防使用抗菌药物的合理率,使我院抗菌药物使用更加规范、合理。
英文摘要: OBJECTIVE: To provide reference for rational prophylactic use of antibacterial drugs in cesarean section. METHODS: Retrospective investigation used in analyzing the use of antibacterial drugs between 472 patients underwent cesarean section 0.5-2 h before the operation from Jan to Dec. in 2013 and 431 patients after umbilical cord clamp during cesarean section from Jan. to Dec. in 2014. RESULTS: After intervention, the reasonable rate of the opportunity to use prophylactic antibacterial drugs was 100%, the reasonable rate of selected drugs varieties increased from 64.41% to 93.50%, and the rate of reasonable treatment course increased from 50.21% to 92.11%, that of usage and dosage also had a noticeable improvement, with statistical significance compared to before intervention (P<0.05). Antibacterial cost per capita decreased from (103.25±13.62)yuan to (54.61±27.21)yuan after intervention, and hospitalization cost per capita decreased from (5 574.8±117.6)yuan to (5 427.4±106.7)yuan, with statistical significance compared to before intervention(P<0.05). CONCLUSIONS: Clinical pharmacists can improve the reasonable rate of antibacterial drugs for prophylactic use in cesarean section by pharmaceutical intervention, it can make the use of antibacterial drugs more standardized and reasonable.
期刊: 2016年第27卷第11期
作者: 金灿,姚晓燕,朱玲仙
英文作者: JIN Can,YAO Xiaoyan,ZHU Lingxian
关键字: 剖宫产;抗菌药物;预防用药;合理用药
KEYWORDS: Cesarean section; Antibacterial drugs; Prophylattic use; Rational use of drug
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