儿童急性阑尾炎围术期抗菌药物合理应用的干预研究 点击下载
论文标题: 儿童急性阑尾炎围术期抗菌药物合理应用的干预研究
英文标题:
中文摘要: 目的:为儿科临床合理应用抗菌药物提供参考。方法:采用回顾性分析方法,选取我院2011年7月-2013年6月(干预前)485例和2013年7月-2015年6月(干预后)503例急性阑尾炎患儿的出院病历,对其围术期抗菌药物应用的合理性进行对比分析。结果:经综合干预后,我院急性阑尾炎患儿围术期抗菌药物品种选择、联合用药和药物更换的合理率分别由干预前的67.42%、80.82%、80.21%上升至94.23%、93.24%、88.27%,用药疗程由干预前的(10.19±3.49)d缩短至(7.83±3.15)d,病程记录中有用药分析的比例由干预前的83.09%上升至89.86%,差异均有统计学意义(P<0.05);而给药剂量、给药频次的合理率虽有所上升,但差异无统计学意义(P>0.05)。结论:采取综合干预措施,可提高围术期抗菌药物应用的合理性,对规范儿科围术期抗菌药物的合理应用具有一定的借鉴作用,我院急性阑尾炎患儿围术期抗菌药物不合理使用的现象仍不容乐观,有待进一步持续干预。
英文摘要: OBJECTIVE: To provide reference for rational use of antibiotics in pediatric department. METHODS: Retrospective analysis was used to select discharged medical records of 485 children with acute appendicitis from Jul. 2011 to Jun. 2013 (before intervention) and 503 cases from Jul. 2013 to Jun. 2015 (after intervention), compare and analyze the rational use of antibiotics in perioperative period. RESULTS: After intervention, the rational rates of antibiotic selection, combined medication and replacement drugs of children with acute appendicitis in our hospital increased from 67.42%, 80.82%, 80.21% to 94.23%, 93.24%, 88.27%, medication course decreased from (10.19±3.49) d to (7.83±3.15) d, the percentage of medication analysis in progress note increased from 83.09% to 89.86%, the differences were statistically significant (P<0.05); though rational rate of dosage and frequency increased, the difference was no statistically significant (P>0.05). CONCLUSIONS: Comprehensive intervention can obviously improve the rational use of perioperative antibiotics, and also play a reference role in standardizing the rational use of perioperative antibiotics in pediatric department. The irrational use of antibiotics in perioperative period in our hospital is still not optimistic, which needs further intervention.
期刊: 2016年第27卷第32期
作者: 曹松山,陶兴茹,裴保方,段彦彦,刘晓玲,陈海燕
英文作者: CAO Songshan,TAO Xingru,PEI Baofang,DUAN Yanyan,LIU Xiaoling,CHEN Haiyan
关键字: 儿童;急性阑尾炎;围术期;抗菌药物;合理用药;干预
KEYWORDS: Children; Acute appendicitis; Perioperative period; Antibiotics; Rational drug use; Intervention
总下载数: 81次
本日下载数: 2次
本月下载数: 81次
文件大小: 619.60Kb

* 注:未经本站明确许可,任何网站不得非法盗链资源下载连接及抄袭本站原创内容资源!在此感谢您的支持与合作!