我国县级医院抗菌药物管理信息化工具应用现状及影响因素分析 点击下载
| 论文标题： | 我国县级医院抗菌药物管理信息化工具应用现状及影响因素分析 |
| 英文标题： | |
| 中文摘要： | 目的 了解我国县级医院抗菌药物管理信息化工具的应用现状，为推进县级医院抗菌药物管理信息化建设提供参考依据。方法于2025年8－9月，采用在线问卷调查方法，对我国31个省（自治区、直辖市）的1007家县级医院开展调查，重点了解抗菌药物使用实时监测系统、处方前置审核系统、不合理使用预警系统和电子处方点评模块（以下分别简称“监测系统“”审核系统”“预警系统“”点评系统”）4种信息化工具应用情况，并运用相关性分析、二元Logistic回归分析探索其影响因素。结果80.83%的县级医院至少配备1种抗菌药物管理信息化工具，19.17%的县级医院未配备任一上述工具，仅18.87%的县级医院配齐了4种工具。监测系统配备率最高（70.80%），预警系统配备率最低（33.96%）。东部地区4种工具的配备均衡且领先，中西部地区审核和预警等干预类工具配备率明显偏低，省内发展差距明显。卫生技术人员总数、医院等级、门诊抗菌药物处方审核率与4种信息化工具的配备率呈显著正相关（P＜0.05）。Logistic回归模型拟合结果显示，审核系统模型评级为“优秀”[受试者工作特征曲线下面积（AUC）为0.81]，预警系统模型评级为“待改进”（AUC＝0.67）。卫生技术人员总数与4种信息化工具的配备率均呈显著正相关（P＜0.05）。结论我国县级医院抗菌药物管理信息化尚处于从“被动统计”向“主动防控”转型的初级阶段，存在结构失衡、区域发展不均等问题。未来需实施差异化支持策略，优化资源配置，提升抗菌药物精细化管理水平。 |
| 英文摘要： | OBJECTIVE To investigate the current status of informatization tools applied to antimicrobial stewardship in county hospitals in China， and to provide a reference for promoting the informatization development of antimicrobial stewardship in county hospitals.METHODS From August to September 2025， an online questionnaire survey was conducted among 1 007 county hospitals across 31 provinces（autonomous regions， and municipalities） in China. The survey focused on the application of four types of informatization tools：the real-time monitoring system for antimicrobial use， the pre-prescription review system， the irrational use warning system， and the electronic prescription evaluation system（hereinafter referred to as the “monitoring system”“review system”“warning system”“evaluation system”，respectively）. Correlation analysis and binary Logistic regression analysis were employed to explore the influencing factors.RESULTS Of the county hospitals， 80.83% were equipped with at least one type of informatization tool for antimicrobial stewardship， while 19.17% had no relevant tool. Only 18.87% of the hospitals were equipped with all four types of tools. The monitoring system exhibited the highest equipped rate （70.80%）， whereas the warning system was equipped in only 33.96% of the hospitals. Four types of tools are evenly and adequately deployed in the eastern region， the central and western regions have far lower deployment rates of intervention tools including review system and warning system， accompanied by prominent intra-provincial gaps. The total number of the health technicians， hospital grade， and prescription review rate of outpatient antibacterial drug were significantly and positively correlated with the deployment rates of the four informatization tools （ P ＜0.05）. The results of the Logistic regression model fitting indicated that the model of the review system was rated “excellent” [area under the receiver operating characteristic curve （AUC）＝0.81]， and the model of the warning system was rated “further improvement” （AUC＝0.67）. The total number of health technicians was significantly positively correlated with the deployment rates of all four types of informatization tools （all P ＜0.05）.CONCLUSIONS The informatization of antimicrobial stewardship in county hospitals in China remains in the initial stage of transitioning from “passive statistics” to “active prevention and control”， with challenges such as structural imbalance and regional disparities. In the future， differentiated support strategies should be implemented， the allocation of resources should be optimized， to enhance the level of refined antimicrobial stewardship. |
| 期刊： | 2026年第37卷第16期 |
| 作者： | 府裕琦；李馨；李颖；吴红卫；樊智鑫；刘锦如；陈熙；夏玉香；孙强；赵颖波 |
| 英文作者： | FU Yuqi， LI Xin，LI Ying，WU Hongwei，FAN Zhixin，LIU Jinru，CHEN Xi，XIA Yuxiang，SUN Qiang，ZHAO Yingbo |
| 关键字： | 信息化工具；县级医院；抗菌药物管理；问卷调查；影响因素 |
| KEYWORDS： | informatization tools;county hospitals;antimicrobial stewardship;Questionnaire survey;Influencing factors |
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